Indian
J Physiol Pharmacol 2003; 325 - 331
Effect
of acute and chronic conditions of over crowding on free
choice ethanol intake in rats
H. S. Nagaraja* and P. S. jeganathan
Department of Physiology,
Kasturba Medical College,
Center for Basic Sciences,
Bejai, Mangalore 575 004
( Received of January 14, 2003 )
(click
here for full text in pdf version)
Abstract
Male albino rats of
Wistar strain were exposed to overcrowding stress in two different
groups for a period of seven days. One group of rats was kept
under stress for six hours per day (acute stressed group)
and the other group rats was kept under stress continuously
(chronic stressed group). The effect of these acute and chronic
stresses on voluntary alcohol (2% w/v) intake was monitored
during the 7 days of stress exposure, and ethanol preference
and total ethanol intake in terms of g/kg body weight were
also studied. A significant increase in ethanol preference
and ethanol intake was observed in oneday and 7 days
chronic stressed group. No significant increase in ethanol
intake was observed in acute stress. Thus a short lasting
stressor may not increase ethanol drinking behavior,
whereas when animals were exposed to more intense stressor
continuously for 7 days, an increase in voluntary drinking
behavior may be seen.