Mid
latency and slow vertex responses during pregnancy
Asha Yadav*, O. P. Tandon and Neelam Vaney
Department of Physiology,
University College of Medical Sciences & GTB Hospital,
Dilshad Garden, Delhi 110 095
( Received on January 7, 2003 )
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Abstract
Central auditory pathways
picked up electro-physiologically as mid latency responses
(MLRs) and slow vertex responses (SVRs) have been studied
least in women during their critical periods of life although
auditory brainstem responses (ABRs) have been studied by many
researchers. In the present study MLRs and SVRs were recorded
in 20 pregnant women of age group 1828 years. Their
period of gestation ranged between 2640 weeks and pregnancy
had been uneventful and normal. MLRs and SVRs were recorded
from Cz-A1 and Cz-A2 positions with alternating 90 dB sound
pressure click stimuli delivered at 5 Hz and 0.5 Hz respectively.
256 stimuli for mid-latency and 64 stimuli for slow vertex
responses were averaged and analyzed. Different waves of these
auditory evoked responses were compared with 20 age matched
non-pregnant females. The data obtained was analyzed for each
variable by using unpaired students T test.Present study
did not reveal any difference in MLR waves during pregnancy
when compared with the non-pregnant females whereas all the
SVR waves were found to be significantly delayed in pregnant
females. As SVR generators are found in different cortical
areas, it can be said that auditory information processing
at the higher centers is slow during pregnancy which in turn
could be due to elevated levels of sex hormones specially
estrogen and progesterone during pregnancy.